Tagged with " 3D Bioprinter"

3D Printing Organs

Once upon a time, the concept of 3D printing organs was only in the imaginations of mad science fiction writers. Today, breakthroughs in 3D organ printing, also called bioprinting, are moving along at a faster clip than humans might ever have imagined.
(…weiter auf lpfrg.com)

Design Student Creates 3D Skin Printer Concept to Alleviate Burns & Skin Disease

Many of us completely take our skin–generally quite durable–for granted, punishing it under the glare of the sun, caking it with makeup, and subjecting it to a wide array of materials and chemicals, generally without a thought. For some though, skin disease and trauma make life itchy, embarrassing, and, in the case of burn victims, devastatingly painful–and they can be potentially life threatening.
(…weiter auf 3dprint.com)

Organovo Describes First Fully Cellular 3D Bioprinted Kidney Tissue

SAN DIEGO, April 1, 2015 /PRNewswire/ — Organovo Holdings, Inc. (NYSE MKT: ONVO) („Organovo“), a three-dimensional biology company focused on delivering breakthrough 3D bioprinting technology, presented data on the company’s in vitro three-dimensional kidney tissue at the 2015 Experimental Biology conference in Boston, Massachusetts.

„Kidney represents an ideal extension of Organovo’s capabilities to 3D bioprint organ tissues that can be tremendously useful in pharmaceutical research,“ said Keith Murphy, Chairman and Chief Executive Officer at Organovo. „The results released today admirably demonstrate a proof of concept that kidney is on the way to becoming another core commercial tissue for Organovo. The product that we intend to build from these initial results can be an excellent expansion for our core customers in toxicology, who regularly express to us an interest in having better solutions for the assessment of human kidney toxicity.“

For the first time, fully human kidney proximal tubular tissues have been generated that are three-dimensional, and consist of multiple tissue-relevant cell types arranged to recapitulate the renal tubular / interstitial interface. The tissues are fabricated using Organovo’s proprietary NovoGenTM bioprinting platform, and will ultimately join the company’s exVive3DTM Liver tissues to expand the repertoire of physiologically-relevant tissue systems available for toxicity and efficacy testing as well as disease modeling. Dr. Sharon Presnell, Chief Technology Officer and Executive Vice President of Research and Development, stated, „Our bioprinted human kidney tissue represents a significant technical advance over the simple monolayer cell line cultures that predominate today. The histologic and functional features of the initial prototypes are compelling, and the in vitro durability of the system will likely enable the assessment of drug effects at chronic, physiologically relevant doses. Furthermore, the cellular complexity of the system will likely support mechanistic investigations into drug responses, including end points that have been difficult or impossible to assess in vitro, including tubular fibrosis and post-injury recovery.“

Key findings and attributes from Organovo’s research include:
(…weiter auf organovo.com)

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