Tagged with " Bioprinter"

3D Printed Drug Delivery System Shows Promise in Countering Transplant Rejection

There has been rapid progression seen in the technology used to 3D print live human cells. Over the last four to five years alone we have seen the technology go from only a concept to having several valuable applications. In fact Organovo is already selling 3D printed human liver tissue to the pharmaceutical industry for drug toxicity testing, with their ultimate goal being the 3D printing of entire human organs for transplant.
(…weiter auf 3dprint.com)

Increasing the viability of bio-printing human cells

The rapid development of viable inkjet technology for highly specialised applications, such as printing human cells, continues to generate significant interest. If successful, the realisation of this technology for specialised biological applications, generally known as ‚biofabrication‘, has the potential to replace the long established (and often controversial) process of using animals for testing new drugs. However, there are many challenges to overcome to enable the successful production of a valve-based cell printer for the formation of human embryonic stem cell spheroid aggregates. For example, printing techniques need to be developed which are both controllable and less harmful to the process of preserving human cell tissue viability and functions.
(…weiter auf industrialtechnology.co.uk)

Synthetisches DNA-Gel für den Druck künstlicher Organe entwickelt

Ein zweiteiliges wasserbasiertes Gel aus synthetischer DNA und Polypeptiden bringt den 3D-Biodrucker weiter in Richtung Druck von Organen für die Transplantation oder als Tiermodell. Dongsheng Liu (Tsinghua-Universität Peking) und Will Shu (Heriot-Watt University Edinburgh) und ihre Arbeitsgruppen sahen sich mit den Hauptschwierigkeiten konfrontiert, zum einen eine geeignete Matrix oder ein Gerüst zu finden, das die lebenden Zellen dreidimensional unterstützt, zum anderen, ein konsistentes Produkt herzustellen, das der Empfänger des Spenderorgans nicht wieder abstößt.
(…weiter auf analytik-news.de)

Can 3-D Printing of Living Tissue Speed Up Drug Development?

Small firm believes bioprinting of human tissue can lower the cost of testing new drugs

Every year, the pharmaceutical industry spends more than $50 billion on research and development. But the path to drug approval by the Food and Drug Administration is laden with abrupt failures in late-phase testing. Only one in 5,000 drugs will make it to market, according to one estimate.

One small biology company believes it has a solution to the pipeline problem: 3-D printing.
(…weiter auf wsj.com)

Will 3D printers, bioprinters change the future of surgery?

Bioprinted organs would not look like those studied in anatomy books

When an MRI revealed a golf ball-sized tumour growing in Pamela Shavaun Scott’s skull, the California psychotherapist turned to a 3D printer to help find the least invasive and risky way for doctors to extract it.

Her husband, Michael Balzer, the founder of a 3D printing service company, used her medical records to create a three-dimensional image of her brain on his computer and print a 3D model of it.
(…weiter auf cbc.ca)

RBCC Joint Venture Partner n3D to Present Latest 3D Bioprinting Research in Washington, D.C.

MIRAMAR BEACH, Fla.–(BUSINESS WIRE)–
Rainbow Coral Corp.’s (RBCC) 3D bioprinting joint venture partner Nano3D Biosciences (n3D) will present a new abstract detailing the latest breakthroughs made using its technology in Washington, D.C. on Wednesday at the 4th annual Society for Laboratory Automation and Screening Conference and Exhibition (SLAS2015).
(…weiter auf finance.yahoo.com)

Using 3D Printing, MakerBot and Feinstein Institute for Medical Research Create Cartilage to Repair Tracheal Damage

Results are showcased at 51st Annual Meeting of The Society of Thoracic Surgeons

San Diego, CA – Investigators at The Feinstein Institute for Medical Research have made a medical breakthrough using 3D printing on a MakerBot® Replicator® 2X Experimental 3D Printer to create cartilage designed for tracheal repair or replacement. The results were reported today at the 51st Annual Meeting of The Society of Thoracic Surgeons in San Diego, in a presentation by Todd Goldstein, an investigator at the Feinstein Institute, part of the North Shore-LIJ Health System. This is a first for medical research where regular MakerBot PLA Filament was used to 3D print a custom tracheal scaffolding, which was combined with living cells to create a tracheal segment.
(…weiter auf feinsteininstitute.org)

MakerBot Stories | A New Frontier in Tracheal Repair

Your trachea, or windpipe, connects the throat and lungs. Air comes in through the windpipe; carbon dioxide goes out.

If it is torn or diseased, surgeons have two ways to fix it. They can remove the damaged part and attach the healthy ends, but there’s only so much slack. Or they can extract some rib cartilage and graft it into the windpipe, which is also made of cartilage. Additional surgery has risks, however. So some patients can’t be helped.
(…weiter auf makerbot.com)

MakerBot Stories | Feinstein Institute for Medical Research

MakerBot Stories | Feinstein Institute for Medical Research from MakerBot on Vimeo.

A team of surgeons and scientists at the Feinstein Institute of Medical Research, the research branch of the North Shore-LIJ Health System, has grown cartilage on a 3D printed scaffolding, pointing the way to custom repairs for damaged and diseased tracheas, or windpipes. The cells grow on a scaffolding created from ordinary MakerBot PLA Filament on a MakerBot Replicator 2X Experimental 3D Printer. “3D printing and tissue engineering have the potential to replace lots of different parts of the human body,” says Dr. Lee Smith, a pediatric otolargyngologist who participated in the research. “The potential for creating replacement parts is almost limitless.”
(Quelle: Vimeo)

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